The clinical consequences of these plaques vary ... of the carotid plaque modifies with the progression of the disease and some phases appear to be more prone to acute vascular events than others; in fact, lesion types IV, V and VI are those typically involved in cerebrovascular events. Moreover, the consequences of a plaque disruption depend not only on the “solid state” of the atheroma itself, but also on the “fluid phase of blood, for example the concentrations of fibrinogen, Atherosclerosis is a disease in which the wall of the artery develops abnormalities, called lesions. The thrombotic response to a plaque rupture is probably regu-lated by the thrombogenicity of the exposed plaque constit- • Acute plaque change. Learn about the symptoms, causes, diagnosis, and treatment of this life-threatening condition. Consequences of plaque rupture. The term acute coronary syndromes (ACS) refers to the spectrum of conditions compatible with acute myocardial ischemia, from unstable angina to acute myocardial infarction (MI). List and draw the characteristic changes in the electrocardiogram seen in myocardial Coronary artery atherosclerosis is the major cause of mortality and morbidity in the industrialised world. Acute narrowing of the vessel lumen: When the plaque ruptures, it will release its pro-coagulants in the bloodstream and that will lead to the formation of thrombus at the rupture site. Indirect data from clinical trials involving hypocholestremic drugs and avoidance of risk factors provide strong support for this new paradigm. Acute myocardial infarction (MI) indicates irreversible myocardial injury resulting in necrosis of a significant portion of myocardium (generally >1 cm). This study sought to investigate the clinical consequences and predictive factors of the Lung injury and acute respiratory distress syndrome have taken center stage as the most dreaded complications of COVID-19, the disease caused by the new coronavirus, SARS-CoV-2. Thrombolytic treatment. of acute coronary syndromes. A 15 month old girl presented to the emergency department with a one week history of unsteady gait and approximately three to four unexplained falls each day. Acute coronary syndrome (ACS) is precipitated by an abrupt change in an atheromatous plaque and/or thrombotic occlusion. Monocyte-derived macrophages recruited into developing ather … 11. Abstract: The pathogenesis of the acute coronary syndrome (ACS) is very complex and not fully clarified, bringing in front the questions regarding the differences between acute coronary syndrome with ST segment elevation (STEMI) and the one without ST segment elevation (UA/NSTEMI), because there isn’t always a ruptured plaque beneath all coronary thrombi. and clinical consequences Describe and explain the role of fixed coronary obstruction, acute plaque change, coronary thrombosis and vasoconstriction in the pathogenesis of ischemic heart disease. One of the aims of secondary prevention is to achieve plaque stabilization. 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